By Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park
This publication presents crucial, the world over appropriate info within the region of orthopedic pathology with emphasis on useful diagnostic features, together with many illustrations: roentgenograms, CT-scans, MRI, scintigraphies, in addition to images of gross surgical specimens and microphotographs, immunohistochemical reactions and genomics. info on histopathological and molecular prognosis, and simple healing directions are supplied.
This ebook bargains beneficiant assurance of epidemiology, scientific beneficial properties, radiology, pathology, differential prognosis and therapy, not just for universal lesions, but additionally these much less often encountered. Clues within the pictures and histopathology had to arrive at a pointy differential analysis are mentioned. The content material is prepared according to the realm well-being Organization’s Consensus class, with the addition of different lesions no longer integrated therein.
Tumors and Tumor-Like Lesions of Bone is aimed toward basic and specialized surgical pathologists, radiologists, orthopedic surgeons, and oncologists, in perform and in training.
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Extra resources for Tumors and Tumor-Like Lesions of Bone: For Surgical Pathologists, Orthopedic Surgeons and Radiologists
CT has replaced fluoroscopic guidance in most institutions as the modality of choice, often with the use of low-dose techniques to limit radiation exposure. Nearly all primary and metastatic bone tumors are visible on CT, which allows for accurate needle positioning within the lesion. In very rare cases, however, bone marrow lesions may not be visualized on CT despite obvious findings on MRI or PET. In these cases, MRI can be a safe and reliable alternative for guiding the biopsy which requires MR-safe equipment and expertise.
The association of multiple NOFs and café au lait spots has been termed JaffeCampanacci syndrome. Severe cases can have mental retardation, cardiovascular and ocular abnormalities, and cryptorchidism. Fibrous Dysplasia Fibrous dysplasia is a nonhereditary benign disorder of bone remodeling that results in marrow replacement by fibroosseous tissue. There is no gender predominance, and lesions, which are intramedullary, can be detected at any age. Fibrous dysplasia can be monostotic or polyostotic, with monostotic fibrous dysplasia being six to ten times more common.
When residual or recurrent tumor is suspected, contrast-enhanced sequences are of value. Bone Scintigraphy Bone scintigraphy uses Tc99m-labeled diphosphonates that bind to hydroxyapatite at sites of osteoblastic activity, resulting in increased radionuclide uptake at areas of bone turnover. This uptake is nonspecific and occurs in many benign and malignant bone tumors along with fractures, osteomyelitis, and other nonneoplastic conditions. Abnormal bone scans should therefore always be correlated with clinical information and other imaging studies.
Tumors and Tumor-Like Lesions of Bone: For Surgical Pathologists, Orthopedic Surgeons and Radiologists by Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park